About TWK10

One strain for muscle health — proven as both a probiotic and a postbiotic.

 

TWK10® (Lactiplantibacillus plantarum TWK10) is a patented probiotic strain isolated from traditional Taiwanese fermented cabbage. It is supplied in both live (probiotic) and heat-killed (postbiotic) forms and is studied primarily for muscle health, exercise performance and age-related muscle maintenance, through the gut–muscle axis.


 

Origin and identification

TWK10® was isolated from traditional Taiwanese fermented cabbage and selected from a panel of lactic-acid-bacteria candidates. Originally designated Lactobacillus plantarum TWK10, it was reclassified as Lactiplantibacillus plantarum under the 2020 taxonomic revision; both names refer to the same strain. Its genome has been fully sequenced and characterized.


Two forms, both clinically studied

TWK10® is supplied as a live probiotic and as a heat-killed postbiotic. Both forms have been evaluated in human clinical trials for exercise performance and body composition — a completeness few single strains offer. Typical daily amounts are 10 billion CFU (live) and 30 billion cells (postbiotic); final intake follows product labelling.


Research and recognition

TWK10® is supported by 27 peer-reviewed publications since 2012, including 9 human clinical trials, and holds multiple patents and 19 international awards.


 

Applications

TWK10® is a clinically studied probiotic strain targeting skeletal muscle health through the gut–muscle axis. While initially recognized for improving exercise performance, emerging evidence supports broader applications spanning healthy aging, GLP-1 companion nutrition, and women's health. This shared biological pathway enables one scientifically validated strain to support multiple product concepts across different life stages and market segments.

 

References

  1. Huang W-C, et al. Nutrients. 2019;11(11):2836.
  2. Lee C-C, et al. Different impacts of heat-killed and viable TWK10 in humans. Microorganisms. 2022;10(11):2181.
  3. Hsu H-Y, et al. Safety assessment of TWK10. Microorganisms. 2022;10(4):784.
  4. Patent and certification list — official documentation to be supplied.