SynForU™-ReMain FAQ

Straight answers about SynForU™-ReMain, for brands and formulators.

Q What is SynForU-ReMain?
A
SynForU-ReMain is a patented, clinically studied two-strain probiotic formula for kidney health, developed by SynbioTech. It works through the gut–kidney axis to reduce gut-derived uremic toxins and support kidney function.
About SynForU-ReMain →
Q How does SynForU-ReMain support the kidneys?
A
It works from the gut. By lowering the gut precursors of uremic toxins, rebalancing the gut microbiota, strengthening the gut barrier, and restoring antioxidant defense, it eases the toxin burden that drives kidney decline.
The Gut–Kidney Axis →
Q What is the gut–kidney axis?
A
The gut–kidney axis is the two-way relationship between the gut microbiota and kidney health: an unbalanced gut produces more toxins, and a leakier gut barrier lets them reach the blood, adding load to the kidney.
The Gut–Kidney Axis →
Q What strains are in SynForU-ReMain?
A
Two: Lacticaseibacillus paracasei LPC1411 (MFM 18) and Lactiplantibacillus plantarum LP1410 (MFM 30-3), selected for clearing the gut precursors of indoxyl sulfate and p-cresyl sulfate.
Q What are gut-derived uremic toxins?
A
They are toxins such as indoxyl sulfate and p-cresyl sulfate that gut bacteria generate from dietary protein; they build up as kidneys decline and further damage kidney tissue.
Q Is SynForU-ReMain clinically studied?
A
Yes. It is supported by four peer-reviewed publications, including a human pilot study in kidney-transplant recipients and two feline CKD studies.
The Science and Recognition Behind of SynForU-ReMain →
Q What did the human study find?
A
In a small pilot, transplant recipients with stable grafts who took the formula for three months showed a modest, statistically significant improvement in creatinine and eGFR, while a comparison group worsened. The findings are preliminary.
Q Is it proven to treat kidney disease?
A
No. SynForU-ReMain is a probiotic ingredient for supporting kidney health, not a drug or a treatment for kidney disease; final product claims depend on local regulations.
Q What is the recommended dosage?
A
A typical daily dose is around 10 billion CFU, adjustable to the format and target market.
Q What formats does it come in?
A
SynForU-ReMain can be formulated as pre-blend powder, stick-pack sachets, and capsules.
Q What consumer groups can SynForU-ReMain be positioned for?
A
SynForU-ReMain can support product concepts targeting proactive healthy aging, kidney and metabolic wellness, and consumers with lifestyle-related metabolic concerns. Final positioning and claims should be adapted to local regulations.
Q Is SynForU-ReMain patented?
A
Yes. It is protected by invention patents in Taiwan (I770811) and the United States (US 12,220,436 B2).
The Science and Recognition Behind of SynForU-ReMain →
Q Has it won awards?
A
Yes. It has earned multiple international invention awards between 2022 and 2025, including Taiwan’s National Innovation Award and 2025 recognition in Japan, the USA, and Africa.
The Science and Recognition Behind of SynForU-ReMain →
Q Can SynForU-ReMain be used in combination formulas?
A
Yes. SynForU-ReMain can be incorporated into multi-ingredient formulations depending on the target positioning, dosage form, stability requirements, and applicable regulations. Contact our technical team for formulation support.
Q What technical documentation is available?
A
SynbioTech can provide supporting documentation including strain information, study summaries, specifications, and technical materials for qualified business partners. Availability may vary by market.
Q How can brands use or get SynForU-ReMain?
A
SynForU-ReMain is a probiotics ingredient supplied by SynbioTech, with formats and documentation to support product development. Contact us for samples and the technical dossier.

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This page is for B2B communication and education. Local regulations vary by country; customers are responsible for compliance before marketing or making health-related claims.